IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Engineers & Technicians

  Karim ESSABRI

  Jean-Marie GARNIER

  Edouard TROESCH

Scientific services

Molecular biology

The Molecular Biology service is based on a well-established expertise in molecular biology acquired during several years. This service consists of two complementary axes in molecular biology: vector and cloning technologies development, and operating procedure standardization for high-throughput cloning. The service provides strategic advice in term of cloning and gives access to its resources (vectors, protocols, know-how…) to researchers et offers training to engineers, technicians, students and post-doc researchers.

• Molecular biology Service official website

• Current projects

• Collaborations

• Prizes/Awards

  2009

  Inserm

  Innovation Prize

  Jean-Marie GARNIER

• News

• Publications

  • Expression of protein complexes using multiple Escherichia coli protein co-expression systems: A benchmarking study

    Busso D., Peleg Y., Heidebrecht T., Romier C., Jacobovitch Y., Dantes A., Salim L., Troesch E., Schuetz A., Heinemann U., Folkers G.E., Geerlof A., Wilmanns M., Polewacz A., Quedenau C., Bussow K., Adamson R., Blagova E., Walton J., Cartwright J.L., Bird L.E., Owens R.J., Berrow N.S., Wilson K.S., Sussman J.L., Perrakis A., Celie P.H.

    J Struct Biol Aug 2011

  • Huntingtin affinity for partners is not changed by polyglutamine length: aggregation itself triggers aberrant interactions

    Davranche A., Aviolat H., Zeder-Lutz G., Busso D., Altschuh D., Trottier Y., Klein F.A.

    Hum Mol Genet July 15, 2011

  • Robots, pipelines, polyproteins: Enabling multiprotein expression in prokaryotic and eukaryotic cells

    Vijayachandran L.S., Viola C., Garzoni F., Trowitzsch S., Bieniossek C., Chaillet M., Schaffitzel C., Busso D., Romier C., Poterszman A., Richmond T.J., Berger I.

    J Struct Biol Aug 2011

  • RSK2 signaling in brain habenula contributes to place aversion learning

    Darcq E., Koebel P., Del Boca C., Pannetier S., Kirstetter A.S., Garnier J.M., Hanauer A., Befort K., Kieffer B.L.

    Learn Mem Sep 2011

  • Single-chain Fv fragment antibodies selected from an intrabody library as effective mono- or bivalent reagents for in vitro protein detection

    Desplancq D., Rinaldi A.S., Stoessel A., Sibler A.P., Busso D., Oulad-Abdelghani M., Van Regenmortel M.H., Weiss E.

    J Immunol Methods June 30, 2011

  • Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiation.

    Benhaddou A, Keime C, Ye T, Morlon A, Michel I, Jost B, Mengus G, Davidson I.

    Cell Death Differ June 24, 2011

  • Insights into metazoan evolution from alvinella pompejana cDNAs

    Gagniere N., Jollivet D., Boutet I., Brelivet Y., Busso D., Da Silva C., Gaill F., Higuet D., Hourdez S., Knoops B., Lallier F., Leize-Wagner E., Mary J., Moras D., Perrodou E., Rees J.F., Segurens B., Shillito B., Tanguy A., Thierry J.C., Weissenbach J., Wincker P., Zal F., Poch O., Lecompte O.

    BMC Genomics 2010

  • Vectors for recombinational cloning and gene expression in mammalian cells using modified vaccinia virus Ankara

    Pradeau-Aubreton K., Ruff M., Garnier J.M., Schultz P., Drillien R.

    Anal Biochem Sept. 1, 2010

  • A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies

    Abdulrahman W., Uhring M., Kolb-Cheynel I., Garnier J.M., Moras D., Rochel N., Busso D., Poterszman A.

    Anal Biochem Feb. 15, 2009

  • Gene expression profile and response to trastuzumab-docetaxel-based treatment in breast carcinoma.

    Végran F, Boidot R, Coudert B, Fumoleau P, Arnould L, Garnier J, Causeret S, Fraise J, Dembélé D, Lizard-Nacol S.

    Br J Cancer Oct. 20, 2009

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  • Ingénieur En Biologie Moléculaire H/F (H/F)