IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Engineers & Technicians

  Isabelle KOLB-CHEYNEL

  Nathalie TROFFER-CHARLIER

Scientific services

Baculovirus

This service proposes different benefits as recombinant viruses generation, amplification and preservation, as well as a small and large scale production of protein and multi-protein complexes. Baculovirus expression vector system (BEVS) is a powerful and polyvalent tool for recombinant protein expression. Without any danger known for human beings, recombinant baculoviruses allow us to produce a large amount of proteins and protein complexes that are difficult to obtain with other biological systems.

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• Publications

  • A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies

    Abdulrahman W., Uhring M., Kolb-Cheynel I., Garnier J.M., Moras D., Rochel N., Busso D., Poterszman A.

    Anal Biochem Feb. 15, 2009

  • Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH

    Rossignol M., Kolb-Cheynel I., Egly J.M.

    EMBO J. 1997

  • Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH.

    Rossignol M, Kolb-Cheynel I, Egly JM.

    EMBO J April 1, 1997

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