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11 ERC grants
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23 major scientific news

Scientific news

Nuclear receptors 3D structure in the spot light

3D structures of nuclear receptors complexes (RXR-RAR and RXR-VDR) with DNA. Atomic models (RXR in cyan, RAR in blue, VDR in orange and DNA in red) in their cover otained by Small-angle X-ray Scattering.

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Rochel N., Ciesielski F., Godet J., Moman E., Roessle M., Peluso-Iltis C., Moulin M., Haertlein M., Callow P., Mely Y., Svergun D.I., Moras D.

Nat Struct Mol Biol May 2011


April 10, 2011

After ten years, Dino Moras' team has achieved the identification of 3D spatial organisation of three nuclear receptors, specific of vitamin D, retinoic acid and of peroxisomes.

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