Publications
Imprimer la liste complète
-
Isoform-selective HDAC1/6/8 inhibitors with an imidazo-ketopiperazine cap containing stereochemical diversity.
Lecointre B(1), Narozny R(2), Borrello MT(3), Senger J(4), Chakrabarti A(4), Jung M(4), Marek M(5), Romier C(5), Melesina J(6), Sippl W(6), Bischoff L(1), Ganesan A(7).
Philos Trans R Soc Lond B Biol Sci 5 juin 2018.
-
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing.
Simoben CV(1), Robaa D(2), Chakrabarti A(3), Schmidtkunz K(4), Marek M(5), Lancelot J(6), Kannan S(7), Melesina J(8), Shaik TB(9), Pierce RJ(10), Romier C(11), Jung M(12), Sippl W(13).
Molecules 2 mars 2018;23:E566.
-
Microtome-integrated microscope system for high sensitivity tracking of in-resin fluorescence in blocks and ultrathin sections for correlative microscopy.
Lemercier N(1)(2)(3)(4), Middel V(5), Hentsch D(1)(2)(3)(4), Taubert S(1)(2)(3)(4), Takamiya M(5), Beil T(5), Vonesch JL(1)(2)(3)(4), Baumbach T(6), Schultz P(7)(8)(9)(10), Antony C(1)(2)(3)(4)(5), Strahle U(11).
Sci Rep 19 octobre 2017;7:13583.
-
Alkoxyurea-Based Histone Deacetylase Inhibitors Increase Cisplatin Potency in Chemoresistant Cancer Cell Lines.
Stenzel K(1), Hamacher A(1), Hansen FK(1)(2), Gertzen CGW(1), Senger J(3), Marquardt V(1)(4)(5)(6), Marek L(1), Marek M(7), Romier C(7), Remke M(4)(5)(6), Jung M(3), Gohlke H(1), Kassack MU(1), Kurz T(1).
J Med Chem 13 juillet 2017;60:5334-5348.
-
Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups.
Krieger V(1), Hamacher A(1), Gertzen CGW(1), Senger J(2), Zwinderman MRH(3), Marek M(4), Romier C(4), Dekker FJ(3), Kurz T(1), Jung M(2), Gohlke H(1), Kassack MU(1), Hansen FK(1)(5).
J Med Chem 13 juillet 2017;60:5493-5506.
-
Isophthalic Acid-Based HDAC Inhibitors as Potent Inhibitors of HDAC8 from Schistosoma mansoni.
Stenzel K(1), Chakrabarti A(2), Melesina J(3), Hansen FK(1)(4), Lancelot J(5), Herkenhohner S(1), Lungerich B(1), Marek M(6), Romier C(6), Pierce RJ(5), Sippl W(3), Jung M(2), Kurz T(1).
Arch Pharm (Weinheim) Aug 2017;350:e1700096.
-
Histone deacetylase inhibition modulates histone acetylation at gene promoter regions and affects genome-wide gene transcription in Schistosoma mansoni.
Anderson L(1,)(2), Gomes MR(2), daSilva LF(1,)(2), Pereira AD(1,)(2), Mourao MM(3), Romier C(4), Pierce R(5), Verjovski-Almeida S(1,)(2).
PLoS Negl Trop Dis 13 avril 2017;11:e0005539.
