IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Researchers

  Christian BRONNER

  Ali HAMICHE

  Philippe RAMAIN

  Catherine RAMAIN

• Post-Doctoral Fellows

  Abdulkhaleg IBRAHIM

  Chrysa LATRICK

  Khalid OUARARHNI

  Christophe PAPIN

• Phd Students

  Arslan IFTIKHAR

  Maria IGNATYEVA

  Hatem SALEM

• Engineers & Technicians

  Isabelle STOLL

• Collaborateur Occasionnel

  Marc MOUSLI

Functional genomics and cancer

Chromatin and epigenetic regulation

Publications

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• The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity.

  Roulland Y(1), Ouararhni K(2), Naidenov M(3), Ramos L(1), Shuaib M(2), Syed SH(4), Lone IN(4), Boopathi R(4), Fontaine E(1), Papai G(5), Tachiwana H(6), Gautier T(1), Skoufias D(7), Padmanabhan K(8), Bednar J(1), Kurumizaka H(6), Schultz P(5), Angelov D(9), Hamiche A(10), Dimitrov S(11).

  Mol Cell Aug. 18, 2016;63:674-85.

• FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC.

  Charles Richard JL(1,)(2), Shukla MS(1,)(2), Menoni H(2), Ouararhni K(3), Lone IN(2), Roulland Y(1), Papin C(3), Ben Simon E(2), Kundu T(4), Hamiche A(3), Angelov D(2), Dimitrov S(1).

  PLoS Genet July 28, 2016;12:e1006221.

• TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection.

  Benarroch-Popivker D(1), Pisano S(1), Mendez-Bermudez A(2), Lototska L(1), Kaur P(3), Bauwens S(1), Djerbi N(1), Latrick CM(1), Fraisier V(4), Pei B(1), Gay A(1), Jaune E(1), Foucher K(1), Cherfils-Vicini J(1), Aeby E(5), Miron S(6), Londoño-Vallejo A(7), Ye J(8), Le Du MH(6), Wang H(3), Gilson E(9), Giraud-Panis MJ(10).

  Mol Cell Jan. 21, 2016;61:274-86.

• Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation.

  Myrianthopoulos V(1), Cartron PF(2), Liutkevi?i?t? Z(3), Klimašauskas S(3), Matulis D(4), Bronner C(5), Martinet N(6), Mikros E(7).

  Eur J Med Chem May 23, 2016;114:390-6.

• Molecular basis and specificity of H2A.Z-H2B recognition and deposition by the histone chaperone YL1.

  Latrick CM(1), Marek M(2), Ouararhni K(1), Papin C(1), Stoll I(1), Ignatyeva M(1), Obri A(1), Ennifar E(3), Dimitrov S(4), Romier C(2), Hamiche A(1).

  Nat Struct Mol Biol Apr 2016;23:309-16.

• H1-nucleosome interactions and their functional implications.

  Bednar J(1), Hamiche A(2), Dimitrov S(3).

  Biochim Biophys Acta Oct. 23, 2015;1859:436-443.

• Site-Selective Monitoring of the Interaction of the SRA Domain of UHRF1 with Target DNA Sequences Labeled with 2-Aminopurine.

  Greiner VJ(1), Kovalenko L(1,)(2), Humbert N(1), Richert L(1), Birck C(3), Ruff M(3), Zaporozhets OA(2), Dhe-Paganon S(4), Bronner C(1,)(3), Mély Y(1).

  Biochemistry Oct. 6, 2015;54:6012-20.

• Structure and function insights into the NuRD chromatin remodeling complex.

  Torchy MP(1), Hamiche A, Klaholz BP.

  Cell Mol Life Sci Jul 2015;72:2491-507.