Post-Doc - B. Seraphin Team
Reference : POST-DOC B.S.
Offer publication : Jan. 20, 2016
The importance of mRNA decay in regulating and finely tuning gene expression is now well established. Numerous enzymes, RNA binding factors, and protein complexes involved in the various RNA decay pathways have been identified and their function was characterized predominantly in yeast and mammalian cells. However, the impact of regulating mRNA decay on the the transcriptome and on organism physiology remain poorly explored, in particular in mammals. The selected post-doctoral trainee will build on the expertise of the lab in studying mRNA decay to investigate the physiological impact of this process in mammals using transgenic mouse models.
Applications are invited for 2 years with possibilities of extensions.
Candidates must be highly motivated and have a PhD in biological science. Strong knowledge of molecular and cellular biology is required. Hands-on experience with molecular techniques and cell culture is necessary. Prior experience with mice genetic and physiology would be an asset but is not required.
Required skills and abilities
Ability to work independently within a team environment, computer literacy and good communication skills are required. French speaking is NOT a requirement.
The Séraphin team is a leader in the field of eukaryotic RNA decay, RNA processing and protein complex analyses using yeast and mammalian cells as model systems. The team is located in a fully equipped molecular and biochemistry laboratory, and is embedded in a highly collaborative and multidisciplinary environment. The candidate will benefit from an excellent work environment, including various state-of–the art research facilities at IGBMC and at the Mouse clinical Institute. The project will develop in the framework of international collaborations.
Please send your application including a statement of past and future research interests describing research experience and expertise, a complete curriculum vitae, date of availability, and at least two contacts for references (including phone number and email) to Fabienne Mauxion (firstname.lastname@example.org).