Experimental evolution of eukaryotic cells
Dr Giulia RANCATI
A*Star, Institute of medical biology, Singapore
Friday, June 28th 2019 - 11 a.m.
- Auditorium, IGBMC
Hosted by Manuel MENDOZA
My lab strive to understand how eukaryotic cells adapt to extreme chemical or genetic perturbations at the molecular and systems level. My research not only aims at tackling one of the most fundamental biological question but could have tremendous implication into the understanding how cancer cells evolve aggressive phenotypes and how we could therapeutically manipulate them to reduce the incidence of chemotherapy resistance. In particular my research aims at answering questions concerning how cells tinker with their cellular networks to achieve phenotypic variation, how genomic mutations bring about phenotypic innovation and how eukaryotic cells accumulate mutations. In this talk I will briefly describe our past achievements and focus on our next challenges.