Genome architecture and regulation
Pr Julie AHRINGER
The Gurdon Institute, University of Cambridge, United Kingdom
Friday, April 26th 2019 - 11 a.m.
- Auditorium, IGBMC
Hosted by Development and stem cells, Sophie JARRIAULT
A fundamental property of a single animal genome sequence is the ability to give rise to diverse cell types. Differential control of genome architecture - the chromatin structure and spatial arrangement of the genome - establishes gene expression programmes that drive cellular identity, and dysregulation of architecture can cause disease. I will discuss the regulation of different architectural features of the C. elegans genome, such as regulatory elements, broad chromatin domains, and 3D genome organization.