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Embo workshop: Chromatin dynamics and nuclear organization in genome maintenance

dimanche 03 juin - jeudi 07 juin 2018 - Auditorium, IGBMC
Organisé(e) par Evi SOUTOGLOU

Maintenance of genome integrity lies at the heart of cell homeostasis. While DNA repair mechanisms have received significant attention for more than half a century, the contribution of the chromatin environment and nuclear organization to genome maintenance has only begun to emerge over the past decade. It is evident that chromatin, being the actual substrate for repair machineries, is heavily remodeled following damage detection and exerts a key function in both targeting and regulating repair at different genomic loci.

This EMBO Workshop brings together an outstanding group of scientists from around the world, young researchers as well as leaders in the field, to cover the following, emerging topics in chromatin, nuclear organization and genome maintenance (i) DNA repair in distinct nuclear domains, (ii) chromatin motion in response to DNA damage, (iii) histone modifications and nucleosome dynamics following DNA damage and (iv) regulatory functions of transcription and RNA during DNA repair and replication stress.

 

Invited speakers:

Irene Chiolo   University of Southern California, USA

Dipanjan Chowdhury   Dana-Farber Cancer Institute, USA

Fabrizio d’Adda di Fagagna   IFOM-IEO, Italy

Jessica Downs   University of Sussex, UK

Karine Dubrana   CEA Fontenay-aux-Roses, France

Dan Durocher   University of Toronto, Canada

Tamas Fisher   Australian National University, Australia

Catherine Freudenreich   Tufts University, USA

Susan Gasser   Friedrich Miescher Institute, Switzerland

Aaron Goodarzi   University of Calgary, Canada

Roger Greenberg   University of Pennsylvania, USA

Anja Groth   University of Copenhagen, Denmark

Tim Humphrey   University of Oxford, UK

Jacqueline Jacobs   Netherlands Cancer Institute, Netherlands

Gaëlle Legube   Center for Integrative Biology, France

Michael Lisby   University of Copenhagen, Denmark

Niels Mailand   University of Copenhagen, Denmark

Jurgen Marteijn   Erasmus MC, Netherlands

Kyle Miller   University of Texas, USA

Philipp Oberdorffer   National Cancer Institute, USA

Philippe Pasero   Institute of Human Genetics, France

Sophie Polo   Paris Diderot University, France

Brendan Price   Dana-Farber Cancer Institute, USA

Simon Reed   Cardiff University, UK

Rodney Rothstein   Columbia University, USA

Julian Sale   MRC Laboratory of Molecular Biology, UK

Bjoern Schwer   University of California, USA

Evi Soutoglou   IGBMC, France

Jessica Tyler   Weill Cornell Medical College, USA

Haico van Attikum   Leiden University Medical Center, Netherlands

 

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